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Doing Cardio burns the fat, but it is VERY important to do weights to build lean body mass. I do cardio 6 days a week and weights every other day, giving the muscle groups time to rest.
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Beginning weight: 278 
Current weight 192 
Total inches lost up to 1/22/07 75 inches
Total weight lost as of 2/19/07: 86
Starting BMI: 43.5
BMI as of 2/19/07: 32.1
Be ready for the twists, and the unexpected, because you know it will come and try to side track you. It's in those moments that your true character and commitment are tested, how you react is a great indication of how or if your life has truly changed. Brian ~ Biggest Loser Season 3
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